An impactful and safe product which helps improve concentration of attention and reduce anxiety and hyperactivity in children.
The use of antibodies to various antigens as an active ingredient for preparing homeopathic products is a promising approach helping to reduce the symptoms of many diseases and conditions. One of ingredients of this type is antibodies to brain-specific S-100 protein lapine S-100 immune globulin (affinity purified antibodies to brain-specific S-100 protein).
The S-100 protein is essential to the following brain functions:
HOMEOPATHIC FORMULATION CONTAINING LAPINE S-100 IMMUNE GLOBULIN (AFFINITY PURIFIED ANTIBODIES TO BRAIN-SPECIFIC S-100 PROTEIN) INFLUENCES ON S-100-MEDIATED PROCESSES.
S-100 protein is involved in multiple neurotransmitter networks of the body. Through its effects on these networks, the product helps improve concentration of attention, reduce hyperactivity and mitigate anxiety.
One study included experiments in which the need for water consumption was put in conflict with self-preservation behaviour. It evaluated the ability of test animals to suppress the anxiety caused by the fear of punishment, which was delivered every time they attempted to lick water.
Anti-anxiety drugs alleviate anxiety in animals. Experimentally, this is demonstrated by an increase
in the number of punished water intakes.
- animals receiving no treatment with the test drug (control);
- animals treated with the test drug (Brillia);
- animals receiving a different anti-anxiety drug (Diazepam);
- animals receiving Brillia along with an agent that blocks serotonin receptors (Brillia + blocker)
Brillia was observed to reduce anxiety in test animals, whereas its anti-anxiety effect was lowered following its combined use with the serotonin receptor blocker. This suggests that serotonin receptors are involved in the mechanism of action of the test drug.
Santonika is a GMP-certified facility and operates high-quality, well-equipped manufacturing facilities located in Kaunas, Lithuania. Our manufacture lines are equipped with well-known and renowned producers (Bosch, IMA, CAM, Ulhman, Marchesini) and allow us to focus on the production of the following dosage forms:
SANTONIKA IS DEVOTED TO THE MANUFACTURE OF ITS OWN PHARMACEUTICAL PREPARATIONS AS WELL AS PROVIDING CONTRACT MANUFACTURE SERVICES TO SEVERAL OF THE WORLD’S LEADING PHARMACEUTICAL COMPANIES.
The key of Santonika's success is its highly qualified, experienced and trained staff. Compliance with quality standards requires the employees to be committed and diligence with the goal of continuous improvement our qualifications. Due to our internal training system, based on sharing the professional experience and skills from one employee to the other, Santonika's employees acquire specific professional knowledge which is not possible to receive in regular educational institutions.
Santonika's plant is based on the Good Manufacturing Practice (GMP) – high-quality assurance standards that guarantee consistency in developing, manufacturing, investigating preparations so that they would correspond to their purpose, the requirements of the marketing authorization certificate and of the specifications.
Santonika's quality system is adapted to the requirements of national pharmaceutical legislation and complies with applicable EU regulations governing the production of pharmaceutical products. Quality and safety of our production is confirmed by GMP certificates and we make every effort to ensure constant quality and maintenance of GMP standards in our plants.
*p<0.05 compared to placebo
#p<0.001 compared to baseline
*p<0.01 compared to placebo
Multicentre double-blind randomized placebo-controlled study
“The efficacy and safety of Brillia for children
in patients with anxiety disorder”